Entamoeba histolytica Genotype and Outcome of Infection with Evidence for a Link between Parasite
نویسندگان
چکیده
منابع مشابه
Evidence for a link between parasite genotype and outcome of infection with Entamoeba histolytica.
The factors determining whether a person infected with Entamoeba histolytica develops disease remain obscure. To investigate whether the parasite genome contributes to the outcome, we have investigated the distribution of parasite genotypes among E. histolytica-infected individuals in Bangladesh. Samples were obtained from individuals who either were asymptomatic, had diarrhea/dysentery, or had...
متن کاملUse of PCR amplification of tRNA gene-linked short tandem repeats for genotyping Entamoeba histolytica.
We have developed a reliable method for PCR-based genotyping of Entamoeba histolytica based on variation in the numbers of short tandem repeats that are linked to tRNA genes in this species. Species-specific primer pairs were designed that differentiate E. histolytica from E. dispar as well as that reveal intraspecies PCR product length polymorphisms. The primers were tested with samples from d...
متن کاملTissue Invasion by Entamoeba histolytica: Evidence of Genetic Selection and/or DNA Reorganization Events in Organ Tropism
Entamoeba histolytica infection may have various clinical manifestations. Nine out of ten E. histolytica infections remain asymptomatic, while the remainder become invasive and cause disease. The most common form of invasive infection is amebic diarrhea and colitis, whereas the most common extra-intestinal disease is amebic liver abscess. The underlying reasons for the different outcomes are un...
متن کاملDiagnosis and Differentiation of Entamoeba Infection in Makkah Al Mukarramah Using Microscopy and Stool Antigen Detection Kits
Entamoeba histolytica infection is one of the significantly common pathogenic protozoa encountered in Saudi Arabia. Previous reports did not distinguish between E. histolytica and E. dispar as differential diagnosis is essential both for treatment decision and public health knowledge. Studies suggested that stool antigen assays are more sensitive and specific than microscopy for the diagnosis o...
متن کاملEvidence that hyaluronidase is not involved in tissue invasion of the protozoan parasite Entamoeba histolytica.
As previous reports suggested that a hyaluronidase is involved in tissue invasion of Entamoeba histolytica, we searched for such an activity in trophozoite extracts. A hyaluronidase activity was not detectable in long-term cultures or in amoebae freshly passaged through a gerbil liver, as evidenced by four different techniques.
متن کامل